{"id":54,"date":"2016-02-26T18:55:29","date_gmt":"2016-02-26T18:55:29","guid":{"rendered":"http:\/\/centroceci.com.ar\/web\/?page_id=54"},"modified":"2016-02-29T17:09:43","modified_gmt":"2016-02-29T17:09:43","slug":"acerca-de-la-investigacion-clinica","status":"publish","type":"page","link":"http:\/\/centroceci.com.ar\/web\/investigaciones-clinicas\/acerca-de-la-investigacion-clinica\/","title":{"rendered":"Acerca de la Investigaci\u00f3n Cl\u00ednica"},"content":{"rendered":"<p> En el Centro de Estudios en Cardiolog\u00eda Intervencionista (CECI) somos un grupo independiente de investigadores cl\u00ednicos entrenados para brindar soluciones integrales para la realizaci\u00f3n de Investigaci\u00f3n Cl\u00ednica de fase IIIb y IV. <\/p>\n<p>Como Contract Research Organization (CRO), en el CECI contamos con una gran experiencia en el campo de la cardiolog\u00eda. Desde hace 25 a\u00f1os venimos capacit\u00e1ndonos y perfeccion\u00e1ndonos para brindar un servicio completo, desde el dise\u00f1o del protocolo, organizaci\u00f3n y coordinanci\u00f3n log\u00edsitica, management, evaluaci\u00f3n de centros, an\u00e1lisis estad\u00edsitico, redacci\u00f3n de manuscritos y presentaci\u00f3n en congresos y revistas arbitriradas. Como un grupo boutique sabemos que nuestra fuerza es mantener la independencia y la veracidad de los datos para lograr un an\u00e1lisis correcto de la informaci\u00f3n m\u00e9dica que se desprende de ellos. Para ello trabajamos con pasi\u00f3n y profesionalismo. Algunos de los estudios que dise\u00f1amos, organizamos, analizamos y realizamos el manuscrito final, actuando como CRO de punta a punta, fueron:<\/p>\n<p><strong>ERACI I<\/strong><\/p>\n<p>Argentine randomized trial of percutaneous transluminal coronary angioplasty versus coronary artery bypass surgery in multivessel disease (ERACI): in-hospital results and 1-year follow-up.ERACI Group.J Am Coll Cardiol. 1993 Oct;22(4):1060-7.<\/p>\n<p>Three-year follow-up of the Argentine Randomized Trial of Percutaneous Transluminal Coronary Angioplasty Versus Coronary Artery Bypass Surgery in Multivessel Disease (ERACI).J Am Coll Cardiol. 1996 Apr;27(5):1178-84<\/p>\n<p><strong>ERACI II<\/strong><\/p>\n<p>Coronary stenting versus coronary bypass surgery in patients with multiple vessel disease and significant proximal LAD stenosis: results from the ERACI II study. Heart. 2003 Feb;89(2):184-8.<\/p>\n<p>Five-year follow-up of the Argentine randomized trial of coronary angioplasty with stenting versus coronary bypass surgery in patients with multiple vessel disease (ERACI II). J Am Coll Cardiol. 2005 Aug 16;46(4):582-8.<\/p>\n<p><strong>ERACI III<\/strong><\/p>\n<p>Coronary stent thrombosis in the current drug-eluting stent era: insights from the ERACI III trial. J Am Coll Cardiol. 2006 Jan 3;47(1):205-7.<\/p>\n<p>Revascularization strategies of coronary multiple vessel disease in the Drug Eluting Stent Era: one year follow-up results of the ERACI III Trial. EuroIntervention. 2006 May;2(1):53-60.<\/p>\n<p>Late loss of early benefit from drug-eluting stents when compared with bare-metal stents and coronary artery bypass surgery: 3 years follow-up of the ERACI III registry. Eur Heart J. 2007 Sep;28(17):2118-25<\/p>\n<p>Long-term safety and efficacy of percutaneous coronary intervention with stenting and coronary artery bypass surgery for multivessel coronary artery disease: a meta-analysis with 5-year patient-level data from the ARTS, ERACI-II, MASS-II, and SoS trials. Circulation. 2008 Sep 9;118(11):1146-54<\/p>\n<p>Percutaneous coronary intervention with drug-eluting stents versus coronary artery bypass surgery for multivessel coronary artery disease: a meta-analysis of data from the ARTS II, CARDia, ERACIIII, and SYNTAX studies and systematic review of observational data. EuroIntervention. 2010 Jun;6(2):269-76<\/p>\n<p><strong>ERACI IV<\/strong><\/p>\n<p>Second versus first generation DES in multiple vessel disease and unprotected left main stenosis: insights from ERACI IV Study. Minerva Cardioangiol. 2015 Aug;63(4):317-27<\/p>\n<p>Modifying angiographic syntax score according to PCI strategy: lessons learnt from ERACI IV Study Cardiovasc Revasc Med. 2015 Oct-Nov;16(7):418-20.<\/p>\n<p>Second vs. First Generation Drug Eluting Stents in Multiple Vessel Disease and Left Main Stenosis: Two-Year Follow-Up of the Observational, Prospective, Controlled and Multicenter ERACI IV Registry.\u00bb Accepted article ahead of-print.<\/p>\n<p><strong>ORAR I<\/strong><\/p>\n<p>Pilot study of oral rapamycin to prevent restenosis in patients undergoing coronary stent therapy: Argentina Single-Center Study (ORAR Trial). J Invasive Cardiol. 2003 Oct;15(10):581-4.<\/p>\n<p>Role of oral rapamycin to prevent restenosis in patients with de novo lesions undergoing coronary stenting: results of the Argentina single centre study (ORAR trial). Heart. 2005 Nov;91(11):1433-7<\/p>\n<p><strong>ORAR II<\/strong><\/p>\n<p>Oral rapamycin after coronary bare-metal stent implantation to prevent restenosis: the Prospective, Randomized Oral Rapamycin in Argentina (ORAR II) Study. J Am Coll Cardiol. 2006 Apr 18;47(8):1522-9<\/p>\n<p><strong>ORAR III<\/strong><\/p>\n<p>Percutaneous coronary intervention with oral sirolimus and bare metal stents has comparable safety and efficacy to treatment with drug eluting stents, but with significant cost saving: long-term follow-up results from the randomised, controlled ORAR III (Oral Rapamycin in ARgentina) study. EuroIntervention. 2009 Jun;5(2):255-64.<\/p>\n<p>Randomized comparison of cost-saving and effectiveness of oral rapamycin plus bare-metal stents with drug-eluting stents: three-year outcome from the randomized oral rapamycin in Argentina (ORAR) III trial. Catheter Cardiovasc Interv. 2012 Sep 1;80(3):385-94<\/p>\n<p>Comparison of cost-effectiveness of oral rapamycin plus bare-metal stents versus first generation of drug-eluting stents (from the Randomized Oral Rapamycin in Argentina [ORAR] 3 trial). Am J Cardiol. 2014 Mar 1;113(5):815-21.<\/p>\n<p><strong>GRAMI TRIAL<\/strong><\/p>\n<p>In-hospital and late results of coronary stents versus conventional balloon angioplasty in acute myocardial infarction (GRAMI trial). Gianturco-Roubin in Acute Myocardial Infarction.Am J Cardiol. 1998 Jun 1;81(11):1286-91.<\/p>\n<p><strong>OCBAS TRIAL<\/strong><\/p>\n<p>Optimal coronary balloon angioplasty with provisional stenting versus primary stent (OCBAS): immediate and long-term follow-up results. J Am Coll Cardiol. 1998 Nov;32(5):1351-7.<\/p>\n<p>The role of acute wall recoil and late restenosis: results of the OCBAS trial (Optimal Coronary Balloon Angioplasty with Provisional Stenting versus Primary Stent). Int J Cardiovasc Intervent. 2001 Jun;4(2):99-106<\/p>\n<p><strong>LASMAL I<\/strong><\/p>\n<p>Latin American randomized trial of balloon angioplasty vs coronary stenting for small vessels (LASMAL): immediate and long-term results. Am J Med. 2005 Jul;118(7):743-51.<\/p>\n<p><strong>LASMAL II<\/strong><\/p>\n<p>Latin American randomized trial of balloon angioplasty versus coronary stenting in diabetic patients with small vessel reference size (Latin American Small Vessel [LASMAL II] Trial): immediate and long-term results. Am Heart J. 2005 Jul;150(1):188.<\/p>\n<p><strong>EUCATAX<\/strong><\/p>\n<p>Efficacy and safety of a double-coated paclitaxel-eluting coronary stent: the EUCATAX trial. Catheter Cardiovasc Interv. 2011 Feb 15;77(3):335-42<\/p>\n<p><strong>CAMOUFLAGE<\/strong><\/p>\n<p>New coating stent design for patients with high-risk coronary lesions for thrombotic events: early and long-term results of the Camouflage registry. J Invasive Cardiol. 2009 Aug;21(8):378-82.<\/p>\n<p><strong>DEAR<\/strong><\/p>\n<p>One-year outcome of patients with diabetes mellitus after percutaneous coronary intervention with three different revascularization strategies: results from the Diabetic Argentina Registry (DEAR). Cardiovasc Revasc Med. 2012 Sep-Oct;13(5):265-71.<\/p>\n<p>La extensa experiencia en la conducci\u00f3n de estudios cl\u00ednicos tanto a nivel nacional como internacional permite a los clientes tener acceso a importantes expertos alrededor del mundo y al CECI brindar las mejores opciones costo efectivas para lograr los objetivos propuestos. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>En el Centro de Estudios en Cardiolog\u00eda Intervencionista (CECI) somos un grupo independiente de investigadores cl\u00ednicos entrenados para brindar soluciones integrales para la realizaci\u00f3n de Investigaci\u00f3n Cl\u00ednica de fase IIIb y IV. Como Contract Research Organization (CRO), en el CECI contamos con una gran experiencia en el campo de la cardiolog\u00eda. Desde hace 25 a\u00f1os &hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":25,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-fullwidth.php","meta":[],"_links":{"self":[{"href":"http:\/\/centroceci.com.ar\/web\/wp-json\/wp\/v2\/pages\/54"}],"collection":[{"href":"http:\/\/centroceci.com.ar\/web\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/centroceci.com.ar\/web\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/centroceci.com.ar\/web\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/centroceci.com.ar\/web\/wp-json\/wp\/v2\/comments?post=54"}],"version-history":[{"count":3,"href":"http:\/\/centroceci.com.ar\/web\/wp-json\/wp\/v2\/pages\/54\/revisions"}],"predecessor-version":[{"id":99,"href":"http:\/\/centroceci.com.ar\/web\/wp-json\/wp\/v2\/pages\/54\/revisions\/99"}],"up":[{"embeddable":true,"href":"http:\/\/centroceci.com.ar\/web\/wp-json\/wp\/v2\/pages\/25"}],"wp:attachment":[{"href":"http:\/\/centroceci.com.ar\/web\/wp-json\/wp\/v2\/media?parent=54"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}